contact@zeinaalmahayri.com
Pharmacogenomics and Safety pharmacology
Safety Pharmacology and Personalized Medicine,
chapter in “Drug Discovery and Evaluation” Springer Nature, 2023 (in production)
By: Al-Mahayri Z, Nagy M
Pharmacogenomics of Statins in the UAE
Utilizing Pharmacogenomic Data for a Safer Use of Statins for the Emirati Population, Current Vascular Pharmacology, 2024
By: Al-qasrawi M, Al-Mahayri Z, Alblooshi H, Alsafar H, Ali Bassam R
Can our genes affect blood pressure lowering drugs?
Altoum S, Al-Mahayri Z, Ali B, Antihypertensives Associated Adverse Events: A Review of Mechanisms and Pharmacogenomic Evidence,
Frontiers in Pharmacology, 14
Can a genetic test improve the treatment of complex depression?
The Utility of CYP2D6 and CYP2C19 Variants to Guide Pharmacological Treatment in Complex Unipolar Major Depression: A Pilot Longitudinal Study, Psychiatric Quarterly, July 2023
By: Reshma Ramaraj · Zeina N. Al-Mahayri · Reema Saleous · Karim Abdel Aziz Fadwa Al-Mugaddam · Mouza Al-Sabousi· Aysha Alhassani· Noura Ali Al Ahbabi Emmanuel Stip · George P. Patrinos · Bassam R. Ali · Danilo Arnone
Did we learn anything from the pandemic?
Opinion: Pharmacogenomics at the Post-Pandemic: If not now, then when?, Frontiers in Pharmacology, 2022 Sep 26
By Zeina N. Al-Mahayri
Exploring the feasibility of pharmacogenomic testing in the UAE clinics for the first time!
Pharmacogenomics Implementation in Cardiovascular Disease in a Highly Diverse Population: Initial Findings and Lessons Learned from a Pilot Study in United Arab Emirates. Human Genomics, 2022 Sep 25;16(1):42
Al-Mahayri Z, Khasawneh L, Alqasrawi M, Sahar Altoum, Gohar Jamil, Sally Badawi, Dana Hamza, Lizy George, Anwar AlZaabi, Husam Ouda, Fatima Al-Maskari, Juma AlKaabi, George P. Patrinos, Bassam R. Ali
Using epidemiology in pharmacogenomics.
Mendelian Randomization in Pharmacogenomics: The Unforeseen Potentials, Biomedicine and Pharmacotherapy, 2022 Jun;150:112952.
By: Khasawneh L, Al-Mahayri Z N, Ali B R.
What are the long term effects of treating childhood leukemia? Do pharmacogenomics have a role to play?
Long-term Effects of Pediatric Acute Lymphoblastic Leukemia Chemotherapy: Can Recent Findings Inform Old Strategies?, Frontiers in Oncology, 2021 By: Al-Mahayri Z, AlAhmad M. & Ali B
Applying pharmacogenomic tests in the clinics globally.
Clinical implementation of drug-metabolizing gene-based therapeutic interventions worldwide, Human Genetics, 2021
By: Tsermpini E, Al-Mahayri Z, Ali B, Patrinos G
How can the chemotherapy toxicity be reduced?
Current opinion on the pharmacogenomics of paclitaxel-induced toxicity. Expert Opin Drug Metab Toxicol, 2021
By: Al-Mahayri Z, AlAhmad M. & Ali B.
Pharmacogenomics in Southeast Asia: an Explorative Study
Pharmacogenetic variants of 100 genes among Southeast Asian populations under the collaboration of SEAPharm network. Human Genome Variation, 2021.
By: Runcharoen C, Fukunaga K, Sensorn I, Iemwimangsa N, Klumsathian S, Tong H, Sy Vo N, Le L, Hlaing T M, Thant M, Zain S M, Mohamed Z, Capule F, Nevado Jr. J, Silao C L, Al-Mahayri Z, Ali B R, et al.
Pharmacogenomic Variability in Healthy Emiratis
Variation in 100 Very Important Pharmacogenes Among Emiratis: Insights from Understudied Populations. Scientific Reports, 2020.
By: Al-Mahayri Z., Patrinos G, Wattanapokayakit S, Iemwimangsa N, Fukunaga K, Mushiroda T, Chantratita W & Ali B
Genes associated with Type I Diabetes in Emiratis
Association of variants in PTPN22, CTLA-4, IL2-RA and INS genes with Type 1 diabetes in Emiratis, Annals of Human Genetics, 2020.
By: Sharma C, Ali B A, Osman W, Afandi B, Aburawi E, Beshyah S, Al-Mahayri Z, Al-Rifai R, Al Yafei Z, ElGhazali G, Alkaabi J.
Pharmacogenomics in Breast Cancer
Toxicity and Pharmacogenomic Biomarkers in Breast Cancer Chemotherapy”. Frontiers in Pharmacology. 2020, 11: 445.
By: Al-Mahayri Z, Patrinos G, & Ali B.
Genetic test to select the right dose of the blood thinner “warfarin”
VKORC1 Variants as Significant Predictors of Warfarin Dose in Emiratis. Pharmacogenomics and Personalized Medicine, 2019, 12: 47-57
By: Al-Mahayri Z*, Al-Jaibeji H, Saab* Y, Souliman K, Al-Gazali L, Patrinos G, Ali B.
Pharmacogenomics is Children Leukemia.
Pharmacogenomics in Pediatric Acute Lymphoblastic Leukemia: Promises and Limitations. Pharmacogenomics, 18(7): 2017-0005 (2017)
By: Al-Mahayri Z, Patrinos G, & Ali B.
Genetics of a rare disorder “Cutis Laxa”
Genotype-phenotype spectrum of PYCR1-related autosomal recessive cutis laxa. Molecular Genetics and Metabolism. November 2013
By: Dimpopoulou A, Fischer B, Gardeitchik T, Schröter P, Kayserili H, Schlack C, Li Y, Brum J, Barisic I, Castori M, Spaich C, Fletcher E, Mahayri Z, et al.
Genetics of Azoospermia
High prevalence of genetic abnormalities in Middle Eastern patients with idiopathic non-obstructive azoospermia. Journal of Assisted Reproduction and Genetics. 2013, 30(6)799
By: Halabi M., Kenj M., Monem F., Mahayri Z., Abou AlChamat G. & Madania A.
Congenital Deafness in Syria
Study of GJB2 Gene Mutations in Syrians with Hearing Loss: High frequency of consanguinity and limited concern of genetic tests. SCLA, 2013, 6(8) [Arabic]
By: Mahayri Z. & Monem F.
Gene mutations related to deafness in Syrians
Screening GJB2 Gene Mutations in Syrians with Sensorineural Hearing Loss, Middle East Journal of Human Genetics. July 2012 – 1 (2): 80–84
By: Mahayri Z. & Monem F.
Cytogenetic tests in Syria
A Review of 1125 cases referred for cytogenetic analysis in Syria. Middle East Journal of Human Genetics. January 2012, 1 (1):35-43 https://oce.ovid.com/article/01607934-201201000-00006/HTML
By: Mahayri Z. & Monem F.